Table 2 Diagnostic accuracy of miRNAs, PCT, and CRP for sepsis
From: Accuracy of circulating microRNAs in diagnosis of sepsis: a systematic review and meta-analysis
| Index | Number of studies | Number of patients | Sen (95% CI) | Spe (95% CI) | PLR (95% CI) | NLR (95% CI) | DOR (95% CI) | AUC (95% CI) | OA (%) |
|---|---|---|---|---|---|---|---|---|---|
| miRNAs | 30 | 3914 | 0.80 (0.75–0.83) | 0.85 (0.80–0.89) | 5.3 (4.0–6.9) | 0.24 (0.20–0.29) | 22 (15–32) | 0.89 (0.86–0.92) | 79.02 |
| PCT | 4 | 347 | 0.73 (0.66–0.79) | 0.86 (0.61–0.96) | 5.2 (1.6–16.8) | 0.31 (0.23–0.43) | 17 (4–68) | 0.74 (0.70–0.77) | 76.95 |
| CPR | 4 | 245 | 0.77 (0.73–0.81) | 0.71 (0.29–0.94) | 2.6 (0.7–9.4) | 0.37 (0.18–0.73) | 7 (1–48) | 0.77 (0.73–0.81) | 61.22 |
| miR-223 | 6 | 732 | 0.77 (0.67–0.84) | 0.91 (0.73–0.97) | 8.3 (2.5–27.9) | 0.25 (0.17–0.38) | 33 (8–142) | 0.87 (0.84–0.90) | 79.25 |