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| |
Total (N = 844)
|
D5W (n = 365)
|
Saline (n = 479)
|
p value
|
|---|
|
Age, years
|
69 (55–77)
|
68 (56–75)
|
69 (55–78)
|
0.313
|
|
Male sex
|
584 (69.2)
|
244 (66.8)
|
340 (71.0)
|
0.202
|
|
Height, cm
|
164 (157–170)
|
164 (158–170)
|
164 (157–170)
|
0.593
|
|
Weight, kg
|
60 (50–70)
|
61 (51–70)
|
60 (50–70)
|
0.62
|
|
Body mass index
|
22 (20–25)
|
23 (20–25)
|
22 (20–25)
|
0.295
|
|
Comorbidity
|
|
Heart failure
|
8 (0.9)
|
2 (0.5)
|
6 (1.3)
|
0.477
|
|
Respiratory failure
|
17 (2.0)
|
5 (1.4)
|
12 (2.5)
|
0.325
|
|
Liver cirrhosis
|
30 (3.6)
|
16 (4.4)
|
14 (2.9)
|
0.266
|
|
Hematologic malignancy
|
45 (5.3)
|
20 (5.5)
|
25 (5.2)
|
0.878
|
|
Metastatic malignancy
|
34 (4.0)
|
12 (3.3)
|
22 (4.6)
|
0.381
|
|
Immunosuppression
|
95 (11.3)
|
39 (10.7)
|
56 (11.7)
|
0.662
|
|
Time from hospitalization to ICU, days
|
2 (0–7)
|
3 (0–8)
|
1 (0–6)
|
0.005
|
|
Patient category
| | | |
0.005
|
|
Planned surgical
|
291 (34.5)
|
150 (41.1)
|
141 (29.4)
| |
|
Nonplanned surgical
|
212 (25.1)
|
83 (22.7)
|
129 (26.9)
| |
|
Medical from ward
|
185 (21.9)
|
75 (20.5)
|
110 (23.0)
| |
|
Medical from ED
|
156 (18.5)
|
57 (15.6)
|
99 (20.7)
| |
|
Main damaged organ
| | | |
0.745
|
|
Cardiovascular
|
342 (40.5)
|
156 (42.7)
|
186 (38.8)
| |
|
Neurologic
|
153 (18.1)
|
65 (17.8)
|
88 (18.4)
| |
|
Respiratory
|
127 (15.0)
|
49 (13.4)
|
78 (16.3)
| |
|
Digestive
|
120 (14.2)
|
51 (14.0)
|
69 (14.4)
| |
|
Other
|
102 (12.1)
|
44 (12.1)
|
58 (12.1)
| |
|
APACHE III score
|
71 (56–88)
|
71 (57–86)
|
72 (54–88)
|
0.916
|
|
Data at ICU admission
|
|
Sodium, mmol/L
|
140 (137–142)
|
140 (137–142)
|
140 (137–143)
|
0.274
|
|
Chloride, mmol/L
|
107 (103–111)
|
108 (104–111)
|
107 (103–111)
|
0.105
|
|
Blood glucose, mg/dL
|
137 (115–169)
|
136 (113–169)
|
138 (115–169)
|
0.525
|
|
Baseline creatinine, mg/dL
|
0.85 (0.74–0.99)
|
0.84 (0.72–0.98)
|
0.85 (0.75–1.00)
|
0.448
|
- Data are presented as median (interquartile range) or number (%)
- APACHE III Acute Physiology and Chronic Health Evaluation III, D5W dextrose 5% in water, ED emergency department, ICU intensive care unit