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Table 1 Characteristics of patients submitted to NIMV as primary ventilatory assistance, stratified according to the response to this method (success or failure) in the prospective cohort

From: Factors associated with non-invasive mechanical ventilation failure in patients with hematological neoplasia and their association with outcomes

Characteristics (n = 59) NIMV failure (n = 30) NIMV success (n = 29) P
Age (years) 50.2 (± 16.7) 53.4 (± 17.4) 0.48
Sex 17 (56.7%) 14 (48.3%) 0.51
Lactate 1.4 (1.1–3.7) 1.4 (1.1–2.2) 0.63
PaO2 upon inclusion (mmHg) 86.1 (73.7–115.9) 80.2 (74.2–109) 0.57
P/F upon inclusion 266.5 (222.8–336.3) 275 (243.5–335) 0.77
SaO2 90 (86.5–95) 92 (90–96.5) 0.11
Overall leukocyte count (cells/mm3) 1020 (150–4233) 1794 (650–9210) 0.07
CRP 261.6 (128.5–361.6) 169.3 (99.5–251.7) 0.09
RR (rpm) 34 (29–39) 29 (27.5–34) 0.042
APACHE II 21 (17–27) 21 (17.5–24) 0.53
SAPS 3 64.5 (53.7–71.2) 63 (55–71) 0.85
SOFA admission 7.0 (5.0–8.2) 5.0 (3.5–7.0) 0.007
Use of vasopressor 27 (90%) 8 (27.6%) < 0.001
Use of ATB 28 (93.3%) 25 (86.2%) 0.36
Use of ATF 24 (80 %) 22 (75.9%) 0.70
Use of corticosteroids 10 (33.3%) 13 (44.9%) 0.36
NT-proBNP 3255 (1055–13727) 4650 (1440–11905) 0.516
Comorbidities
 COPD 4 (13.3%) 2 (6.9%) 0.42
 HF 3 (10%) 7 (24.1%) 0.14
Follow-up data
 HD 3 (10%) 2 (6.9%) 0.66
 CT 17 (56.7%) 12 (40%) 0.24
 Exclusive palliative care 2 (6.7%) 6 (20.7%) 0.11
  1. ATB antibiotics, ATF antifungal, NT-proBNP biomarker portion N-terminal of pro-hormone of B-type natriuretic peptide, COPD chronic obstructive pulmonary disease, HF heart failure, PaO2 arterial pressure of oxygen; P/F PaO2/FIO2 ratios, ICU intensive care unit, NIMV non-invasive mechanical ventilation, SaO2 oxygen saturation, cells/mm3 cells per cubic millimeter, mmHg millimeters of mercury, CRP reactive protein, RR respiratory rate (incursion per minute), APACHE II Acute Physiology and Chronic Health Evaluation II; SAPS 3 Simplified Acute Physiology Score 3, SOFA Sequential Organ Failure Assessment, HD hemodialysis, CT chemotherapy
  2. Except for age, presented as mean ± standard deviation, all continuous variables are presented as median (Q1–Q3). Categorical variables are presented as n (%)
  3. Significance was considered when P < 0.05