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|
Study name
|
Study groups
|
Total number
|
Age
|
Male (%)
|
BMI
|
SAPS II score
|
Respiratory rate
|
PaO2/FiO2 ratio
|
PaCO2
|
|---|
|
Yu 2017
|
HFNC
|
56
|
56.31 ± 7.03
|
54
|
26.32 ± 4.73
|
NA
|
18.43 ± 3.45
|
350 ± 33.87
|
41.73 ± 6.33
|
|
SO
|
54
|
55.82 ± 7.92
|
52
|
25.19 ± 5.02
|
NA
|
17.98 ± 3.87
|
341 ± 40.65
|
43.52 ± 4.93
|
|
Jaber 2016
|
NIV
|
148
|
62.5 ± 14.5
|
78.4
|
27.2 ± 5.9
|
33.6 ± 12.8
|
28.2 + 7.7
|
201 ± 69
|
39 ± 7
|
|
SO
|
145
|
64.4 ± 13.1
|
74.5
|
27.1 ± 6.2
|
33.4 ± 11.7
|
28.8 + 7.3
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188 ± 71
|
37 ± 7
|
|
Gupta 2016
|
HFNC
|
10
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
|
NIV
|
10
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
NA
|
|
Futier 2016
|
HFNC
|
108
|
62 ± 12
|
56
|
25 ± 4
|
NA
|
NA
|
NA
|
NA
|
|
SO
|
112
|
61 ± 13
|
57
|
25 ± 4
|
NA
|
NA
|
NA
|
NA
|
|
Stephan 2015
|
NIV
|
416
|
63.9 (62.6–65.2)
|
67
|
28.2 (27.6–28.7)
|
28.8 (27.7–30.0)
|
23.2 (22.6–24.0)
|
203 (195–212)
|
39.1 (38.4–39.8)
|
|
HFNC
|
414
|
63.8 (62.5–65.2)
|
66
|
28.3 (27.8–28.8)
|
29.0 (27.8–30.1)
|
22.8 (22.1–23.5)
|
196 (187–204)
|
38.7 (38.1–39.4)
|
|
Zhu 2013
|
NIV
|
48
|
62 ± 10.3
|
66
|
25.3 ± 4.6
|
NA
|
28.3 ± 8.6
|
NA
|
38.9 ± 12.2
|
|
SO
|
47
|
61 ± 12.2
|
57
|
24.4 ± 3.5
|
NA
|
25.4 ± 6.7
|
NA
|
38.3 ± 11.3
|
|
Squadrone 2005
|
NIV
|
105
|
66 ± 9
|
68
|
26.5 ± 4.7
|
27 ± 7
|
NA
|
247 ± 33
|
39 ± 7
|
|
SO
|
104
|
65 ± 10
|
62
|
26.3 ± 4.5
|
28 ± 8
| |
255 ± 31
|
39 ± 5
|
|
Aurian 2001
|
NIV
|
24
|
58.9 ± 10
|
NA
|
NA
|
16.9 ± 5.4
|
26.25 ± 13.2
|
124 ± 50.2
|
63.9 ± 20.5
|
|
SO
|
24
|
63 ± 9
|
NA
|
NA
|
16.8 ± 4.4
|
29.5 ± 6.9
|
111 ± 54.3
|
43.4 ± 9.3
|
|
Antonelle 2000
|
NIV
|
20
|
45 ± 19
|
65
|
NA
|
NA
|
38 ± 3
|
NA
|
42 ± 10
|
|
SO
|
20
|
44 ± 10
|
60
|
NA
|
NA
|
37 ± 1
|
NA
|
38 ± 10
|
- Data are provided percent (%), mean ± SD, or median (interquartile range)
- HFNC high-flow nasal cannula, SO standard oxygen, NIV non-invasive ventilation, BMI body mass index, SAPS simplified acute physiology score, PaO2/FiO2 partial pressure of arterial oxygen to fraction of inspired oxygen ratio, PaCO2 partial pressure of arterial carbon dioxide, NA not available