Table 1 Patients’ characteristics
From: A comprehensive protocol for ventilator weaning and extubation: a prospective observational study
| All patients | PERF | Non-PERF | p values | |
|---|---|---|---|---|
| (n = 248) | (n = 24) | (n = 224) | ||
| Age (years) | 65 ± 17 | 64 ± 18 | 65 ± 17 | 0.8 |
| Women, n (%) | 77 (31) | 7 (29) | 70 (31) | 1.0 |
| APACHE II score just before extubation | 13 (10–16) | 12.5 (11–16) | 13 (10–16) | 0.8 |
| SOFAT score just before extubation | 5 (4–6) | 5 (4–6.3) | 5 (4–6) | 0.5 |
| RSBI (breaths/min/L) | 44 ± 21 | 45 ± 18 | 44 ± 21 | 0.9 |
| Duration of mechanical ventilation (days) | 7 (5–11) | 7.5 (5–13.3) | 7 (5–11) | 0.6 |
| Reason for mechanical ventilation, n (%) | 0.2 | |||
| ARDS | 159 (64.1) | 14 (58) | 145 (65) | |
| Congestive heart failure | 57 (23.0) | 5 (21) | 52 (23) | |
| Post-cardiac arrest syndrome | 30 (12.1) | 4 (16) | 26 (12) | |
| COPD exacerbation | 2 (0.8) | 1 (4) | 1 (0.4) | |
| Comorbid diseases, n (%) | 0.4 | |||
| COPD | 17 (7) | 5 (21) | 12 (5) | |
| Coronary artery disease | 35 (14) | 5 (21) | 30 (13) | |
| Chronic heart failure | 25 (10) | 4 (17) | 21 (9) | |
| Chronic renal failure | 14 (6) | 1 (4) | 13 (6) | |
| Diabetes mellitus | 44 (18) | 8 (33) | 36 (16) | |
| Hypertension | 85 (34) | 9 (38) | 76 (34) | |
| Vital signs just before extubation | ||||
| Heart rate (beats/min) | 88 ± 19 | 88 ± 19 | 88 ± 18 | 0.9 |
| MAP (mmHg) | 90 ± 15 | 89 ± 16 | 90 ± 15 | 0.6 |
| RR (breaths/min) | 20 ± 7 | 20 ± 6 | 20 ± 7 | 0.9 |
| ABG values just before extubation | ||||
| pH | 7.45 ± 0.04 | 7.45 ± 0.04 | 7.45 ± 0.04 | 0.5 |
| PaCO2 (mmHg) | 38 ± 6 | 39 ± 5 | 38 ± 6 | 0.5 |
| PaO2/FiO2 | 301 ± 83 | 282 ± 88 | 303 ± 83 | 0.3 |